Metabolic Syndrome Resolution in Children and Adolescents After 10 Weeks of Weight Loss

Abstract

Without aggressive intervention, childhood obesity and the metabolic syndrome may result in lifelong physical consequences. Interventions that emphasize healthy eating and regular exercise are crucial to stop this epidemic and its ramifications. This paper discusses the incidence of the metabolic syndrome and cardiovascular risk factors before and after a weight loss program. A retrospective review was conducted in 135 children and adolescents (aged 6 to 19) who completed a 10-week medically supervised weight loss program. Outcome measures included mean change in each component of the metabolic syndrome, total cholesterol, low-density lipoprotein cholesterol, and hemoglobin A_1c. After 10 weeks of weight loss, a mean (SD) weight loss of 9.24 (19.5) kg was attained. Resolution of the metabolic syndrome was seen in 75.5% of children and adolescents. Weight loss can reverse metabolic syndrome and decrease cardiovascular risk in as little as 10 weeks.