Microstructured reactors for development and production in pharmaceutical and fine chemistry.

V Hessel, P Löb, U Krtschil, H Löwe
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引用次数: 9

Abstract

The true potential of microprocess technology for process intensification is not yet fully clear and needs to be actively explored, although more and more industrial case stories provide information. This paper uses a shortcut cost analysis to show the major cost portions for processes conducted by microstructured reactors. This leads to predicting novel chemical protocol conditions, which are tailored for microprocess technology and which are expected to highly intensify chemical processes. Some generic rules to approach this are termed new process windows, because they constitute a new approach to enabling chemistry. Using such process intensification together with scaled-out microstructured reactors, which is demonstrated by the example of gas-liquid microprocessing, paves the road to viable industrial microflow processes. Several such commercially oriented case studies are given. Without the use of new process windows conditions, microprocess technology will probably stick to niche applications.

用于制药和精细化学开发和生产的微结构反应器。
尽管越来越多的工业案例提供了信息,但微过程技术在过程强化方面的真正潜力尚不完全清楚,需要积极探索。本文采用一种快捷成本分析方法来显示微结构反应器工艺的主要成本部分。这导致预测新的化学协议条件,这是为微过程技术量身定制的,预计将高度强化化学过程。一些通用规则被称为新过程窗口,因为它们构成了实现化学的新方法。以气液微处理为例,将这种工艺强化与按比例放大的微结构反应器相结合,为实现可行的工业微流工艺铺平了道路。给出了几个这样以商业为导向的案例研究。如果不使用新的进程窗口条件,微进程技术可能会局限于特定的应用程序。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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