A new ratiometric molecularly imprinted electrochemical sensor for the detection of Sunset Yellow based on gold nanoparticles

IF 5.4 2区医学 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Biomaterials Science & Engineering Pub Date : 2023-07-01 DOI:10.1016/j.foodchem.2023.135600

Long Wu , Ting Wu , Wei Zeng , Shuhong Zhou , Weimin Zhang , Jing Ma

引用次数: 2

Abstract

Since a high dosage or excessive intake of Sunset Yellow (SY) may pose a threat to human health, it is in great demand to construct an effective method to detect and control SY. Based on the molecularly imprinted polymers (MIPs) and dual-signal output mode, a ratiometric molecularly imprinted electrochemical sensor (RMIECs) was developed for sensitive detection of SY. AuNPs not only provided a large specific surface area to enhance the electron transfer rate but also served as a reference signal (S1), together with SY signal (S2), to produce dual signals. For a proof-of-application study, RMIECs was applied to detect SY with a wide linear range from 10 nM to 100 μM and a low detection limit (LOD) of 1.60 nM (S/N = 3, n = 3). Besides, the method was applied in spiked food samples with recoveries of 94.0 ∼ 97.0 % as well as relative errors of 5.4 ∼ 8.3 %, revealing its promising potential in detection of SY.

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一种新型的基于金纳米颗粒的比例分子印迹电化学日落黄检测传感器

由于高剂量或过量摄入日落黄会对人体健康造成威胁，因此迫切需要建立一种有效的检测和控制日落黄的方法。基于分子印迹聚合物(MIPs)和双信号输出模式，研制了一种用于SY敏感检测的比例型分子印迹电化学传感器(RMIECs)。AuNPs不仅提供了较大的比表面积来提高电子传递速率，而且还作为参考信号(S1)，与SY信号(S2)一起产生双重信号。在应用验证研究中，RMIECs检测SY的线性范围为10 nM ~ 100 μM，检出限(LOD)为1.60 nM (S/N = 3, N = 3)。此外，该方法应用于加标食品样品，回收率为94.0 ~ 97.0%，相对误差为5.4 ~ 8.3%，显示了其在SY检测中的广阔潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Biomaterials Science & Engineering Materials Science-Biomaterials

CiteScore

10.30

自引率

3.40%

发文量

413

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