Development of bioactive substances for functional foods--scientific and other aspects.

Abstract

The discovery and development of bioactive substances and their use in the manufacture of food products has the potential to contribute to the optimal health of populations and in reducing the risk of chronic disease. In assessing the efficacy of these substances in man, the concept of biomarkers could play a key role. However, it is the validation of such biomarkers which is crucial to the eventual availability of foods containing bioactive substances. Determining the safety and efficacy of these substances, and in particular in establishing claims, requires close cooperation between industry, regulatory authorities and the scientific community.