Genovefa D Kolovou, Katherine K Anagnostopoulou, Antonis N Pavlidis, Klelia D Salpea, Stella A Iraklianou, Ioannis S Hoursalas, Dimitri P Mikhailidis, Dennis V Cokkinos
{"title":"Metabolic syndrome and gender differences in postprandial lipaemia.","authors":"Genovefa D Kolovou, Katherine K Anagnostopoulou, Antonis N Pavlidis, Klelia D Salpea, Stella A Iraklianou, Ioannis S Hoursalas, Dimitri P Mikhailidis, Dennis V Cokkinos","doi":"10.1097/01.hjr.0000224490.10845.26","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Postprandial hyperlipidaemia may be a predictor of vascular risk.</p><p><strong>Design: </strong>We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n=41) and women (n=21) with metabolic syndrome (MetS).</p><p><strong>Methods: </strong>Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load.</p><p><strong>Results: </strong>Men showed a greater plasma TG response 8 h after the fat load (284+/-117 versus 224+/-126 mg/dl, P=0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC.</p><p><strong>Conclusions: </strong>Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance.</p>","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":" ","pages":"661-4"},"PeriodicalIF":0.0000,"publicationDate":"2006-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hjr.0000224490.10845.26","citationCount":"16","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Cardiovascular Prevention & Rehabilitation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/01.hjr.0000224490.10845.26","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 16
Abstract
Background: Postprandial hyperlipidaemia may be a predictor of vascular risk.
Design: We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n=41) and women (n=21) with metabolic syndrome (MetS).
Methods: Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load.
Results: Men showed a greater plasma TG response 8 h after the fat load (284+/-117 versus 224+/-126 mg/dl, P=0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC.
Conclusions: Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance.
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