Prevalence of Vitamin D Deficiency among Hemodialysis Patients in Palestine: A Cross-Sectional Study.

IF 1.7 Q3 UROLOGY & NEPHROLOGY

International Journal of Nephrology Pub Date : 2021-03-12 eCollection Date: 2021-01-01 DOI:10.1155/2021/6684276

Zaher A Nazzal, Zakaria Hamdan, Nihal Natour, Maram Barbar, Rawan Rimawi, Eziyeh Salaymeh

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Abstract

Introduction: The level of vitamin D status and its relationship to kidney function and liver function among patients with and without type 2 diabetes were not studied among Palestinian hemodialysis patients before. The aim of this study was to assess the status of vitamin D in hemodialysis patients with and without type 2 diabetes and its determinants.

Methods: Data were collected on 163 patients on hemodialysis therapy in the Nephrology Department at Najah National University Hospital. Information on age, sex, plasma 25 (OH)D, serum calcium, serum phosphate, parathyroid hormone, dialysis period, hypertension, diabetes, ALT, AST, albumin, alkaline phosphates, and BMI was obtained from the medical records. Data were analyzed using SPSS. Findings. The mean level of 25 (OH)D was 17.3 ± 10.5 ng/ml. Only 12.9% of subjects had 25 (OH)D levels >30 ng/ml, whereas 65% had levels between 10 and 30 ng/ml; the remaining 22.1% were severely vitamin D deficient (<10 ng/ml). Vitamin D deficiency was more prevalent among females. It was not related to PTH, calcium, kidney, or liver function tests.

Conclusion: Vitamin D deficiency is highly prevalent among patients on hemodialysis with or without DM2.

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巴勒斯坦血液透析患者维生素 D 缺乏症的患病率：一项横断面研究。

导言：此前，尚未对巴勒斯坦血液透析患者中2型糖尿病患者和非2型糖尿病患者的维生素D水平及其与肾功能和肝功能的关系进行研究。本研究旨在评估患有和未患有 2 型糖尿病的血液透析患者的维生素 D 状况及其决定因素：收集了纳贾国立大学医院肾脏科 163 名血液透析患者的数据。从病历中获取了有关年龄、性别、血浆 25 (OH)D、血清钙、血清磷酸盐、甲状旁腺激素、透析时间、高血压、糖尿病、谷丙转氨酶、谷草转氨酶、白蛋白、碱性磷酸盐和体重指数的信息。数据使用 SPSS 进行分析。研究结果25 (OH)D 的平均水平为 17.3 ± 10.5 纳克/毫升。只有 12.9% 的受试者 25 (OH)D 水平大于 30 纳克/毫升，而 65% 的受试者 25 (OH)D 水平介于 10 至 30 纳克/毫升之间；其余 22.1% 的受试者严重缺乏维生素 D：维生素 D 缺乏在伴有或不伴有 DM2 的血液透析患者中非常普遍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Nephrology UROLOGY & NEPHROLOGY-

CiteScore

3.40

自引率

4.80%

发文量

审稿时长

17 weeks

期刊介绍： International Journal of Nephrology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies focusing on the prevention, diagnosis, and management of kidney diseases and associated disorders. The journal welcomes submissions related to cell biology, developmental biology, genetics, immunology, pathology, pathophysiology of renal disease and progression, clinical nephrology, dialysis, and transplantation.