Super-rapid race for saving lives by developing COVID-19 vaccines.

IF 1.5 Q3 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Anusha Uttarilli, Sridhar Amalakanti, Phaneeswara-Rao Kommoju, Srihari Sharma, Pankaj Goyal, Gowrang Kasaba Manjunath, Vineet Upadhayay, Alisha Parveen, Ravi Tandon, Kumar Suranjit Prasad, Tikam Chand Dakal, Izhar Ben Shlomo, Malik Yousef, Muniasamy Neerathilingam, Abhishek Kumar
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引用次数: 13

Abstract

The pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people and claimed thousands of lives. Starting in China, it is arguably the most precipitous global health calamity of modern times. The entire world has rocked back to fight against the disease and the COVID-19 vaccine is the prime weapon. Even though the conventional vaccine development pipeline usually takes more than a decade, the escalating daily death rates due to COVID-19 infections have resulted in the development of fast-track strategies to bring in the vaccine under a year's time. Governments, companies, and universities have networked to pool resources and have come up with a number of vaccine candidates. Also, international consortia have emerged to address the distribution of successful candidates. Herein, we summarize these unprecedented developments in vaccine science and discuss the types of COVID-19 vaccines, their developmental strategies, and their roles as well as their limitations.

通过开发COVID-19疫苗来拯救生命的超高速竞赛。
由严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2)引起的2019年冠状病毒病(COVID-19)大流行已经影响了数百万人,夺去了数千人的生命。从中国开始,可以说是现代最危险的全球卫生灾难。整个世界都在与这种疾病作斗争,COVID-19疫苗是主要武器。尽管传统的疫苗开发管道通常需要十多年的时间,但由于COVID-19感染导致的每日死亡率不断上升,因此需要制定快速通道战略,以便在一年的时间内开发出疫苗。政府、公司和大学已经联网,汇集资源,并提出了一些候选疫苗。此外,已经出现了国际财团来解决成功候选人的分配问题。在此,我们总结了这些前所未有的疫苗科学进展,并讨论了COVID-19疫苗的类型、开发策略、作用和局限性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Integrative Bioinformatics
Journal of Integrative Bioinformatics Medicine-Medicine (all)
CiteScore
3.10
自引率
5.30%
发文量
27
审稿时长
12 weeks
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