Effect of Ramadan Fasting on Body Composition, Biochemical Profile, and Antioxidant Status in a Sample of Healthy Individuals.

IF 2.1 Q3 ENDOCRINOLOGY & METABOLISM
International Journal of Endocrinology and Metabolism Pub Date : 2020-10-31 eCollection Date: 2020-10-01 DOI:10.5812/ijem.107641
Asna Urooj, Namratha Pai Kotebagilu, Lohith Mysuru Shivanna, Satish Anandan, Akshatha Nagaraja Thantry, Syeda Farha Siraj
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引用次数: 18

Abstract

Background: Muslims fast during the month of Ramadan by abstinence from food and drink every day from dawn to sunset. Studies have reported contradictory results with respect to the changes in body weight and biochemical parameters. No study has been conducted on the association between fasting and body weight and biochemical parameters in the Indian setting on healthy Muslim subjects.

Objectives: To assess the effect of fasting during Ramadan on biochemical parameters such as lipid profile, liver function test, renal function test, antioxidant status, random blood sugar, hemoglobin, body composition, and blood pressure in a sample of healthy individuals.

Methods: In this study, 52 healthy free-living participants (25 males, 27 females, 21-64 years) who met the inclusion and exclusion criteria and completed both follow-ups (before and after Ramadan) were studied. Participants were fasting 12 hours a day for at least 21 days, including menstruating women. It was a free-living study with no dietary restrictions. Anthropometry, lipid profile, liver and renal function tests were measured by standard methods. Body composition was analyzed by bioelectrical impedance.

Results: Significant beneficial changes in albumin, alanine aminotransferase, creatinine, and high-density lipoprotein (HDL) were observed, while total cholesterol, random blood sugar, aspartate aminotransferase, and alkaline phosphatase enzymes remained unchanged after Ramadan. Fasting did bring in some changes in body composition; among both men and women, mean weight loss ranged from 0.81 - 1.4 kg in majority of the subjects, which was due to loss in muscle mass. Moderate changes in intra- and extracellular water content was observed after fasting.

Conclusions: Significant improvements were observed in HDL levels and liver function tests, which can be attributed to the loss of body weight. Improvement in liver function tests may be related to the changes in cytokines and alteration in sleep patterns. Ramadan-like fasting, along with the nutritional education prior to fasting, may be beneficial and effective in the spiritual and overall well-being.

斋月禁食对健康个体身体成分、生化特征和抗氧化状态的影响
背景:穆斯林在斋月期间禁食,每天从黎明到日落都不吃不喝。研究报告了关于体重和生化参数变化的相互矛盾的结果。在印度,没有研究对健康的穆斯林受试者进行禁食与体重和生化参数之间的关系。目的:评估斋月期间禁食对健康人群血脂、肝功能、肾功能、抗氧化状态、随机血糖、血红蛋白、身体成分和血压等生化指标的影响。方法:选取52例符合纳入标准和排除标准的自由生活健康受试者(男性25例,女性27例,年龄21 ~ 64岁),并在斋月前后完成随访。参与者每天禁食12小时,持续至少21天,包括经期妇女。这是一项自由生活的研究,没有饮食限制。采用标准方法测量人体测量、血脂、肝肾功能。用生物电阻抗法分析体成分。结果:斋月后,白蛋白、丙氨酸转氨酶、肌酐和高密度脂蛋白(HDL)发生了显著的有益变化,而总胆固醇、随机血糖、天冬氨酸转氨酶和碱性磷酸酶保持不变。禁食确实给身体成分带来了一些变化;在男性和女性中,大多数受试者的平均体重减轻在0.81 - 1.4公斤之间,这是由于肌肉质量的减少。禁食后观察到细胞内和细胞外含水量的适度变化。结论:在高密度脂蛋白水平和肝功能测试中观察到显著的改善,这可能归因于体重的减轻。肝功能检查的改善可能与细胞因子的变化和睡眠模式的改变有关。像斋月一样的禁食,以及禁食前的营养教育,可能对精神和整体健康有益和有效。
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来源期刊
CiteScore
3.10
自引率
4.80%
发文量
0
期刊介绍: The aim of the International Journal of Endocrinology and Metabolism (IJEM) is to increase knowledge, stimulate research in the field of endocrinology, and promote better management of patients with endocrinological disorders. To achieve this goal, the journal publishes original research papers on human, animal and cell culture studies relevant to endocrinology.
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