Long-term Health Consequences of Endometriosis - Pathways and Mediation by Treatment.

IF 0.7 Q4 OBSTETRICS & GYNECOLOGY

Current Obstetrics and Gynecology Reports Pub Date : 2020-09-01 Epub Date: 2020-05-29 DOI:10.1007/s13669-020-00287-9

Leslie V Farland, Holly R Harris

{"title":"Long-term Health Consequences of Endometriosis - Pathways and Mediation by Treatment.","authors":"Leslie V Farland, Holly R Harris","doi":"10.1007/s13669-020-00287-9","DOIUrl":null,"url":null,"abstract":"Purpose of review: The purpose of this review is to discuss the most up to date research on endometriosis and chronic disease risk, highlighting the role treatments for endometriosis may play in these associations.Recent findings: Previous studies have shown a consistent association between endometriosis and risk for epithelial ovarian cancer but the association with other cancers is less clear. Current research indicates that endometriosis may in be associated with risk of systemic lupus erythematosus, and potentially other autoimmune diseases. Limited evidence is also present for the association between endometriosis and cardiovascular disease and related conditions (e.g,. hypertension, hypercholesterolemia). A potential explanation for a portion of the increased risk of chronic diseases among women with endometriosis may relate to treatments for endometriosis impacting these outcomes.Summary: Given the prevalence of endometriosis, understanding the relation between endometriosis and other chronic diseases has the potential to impact the health of many women. However, few high-quality studies with limited biases and adequate follow-up currently exist. Future multi-disciplinary research in prospective cohorts, with ample follow-up time, and detailed information on endometriosis characteristics and treatment is critical to advancing our understanding of this disease and its consequences.","PeriodicalId":44726,"journal":{"name":"Current Obstetrics and Gynecology Reports","volume":"9 3","pages":"79-88"},"PeriodicalIF":0.7000,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13669-020-00287-9","citationCount":"15","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Obstetrics and Gynecology Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s13669-020-00287-9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/5/29 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}

引用次数: 15

Abstract

Purpose of review: The purpose of this review is to discuss the most up to date research on endometriosis and chronic disease risk, highlighting the role treatments for endometriosis may play in these associations.

Recent findings: Previous studies have shown a consistent association between endometriosis and risk for epithelial ovarian cancer but the association with other cancers is less clear. Current research indicates that endometriosis may in be associated with risk of systemic lupus erythematosus, and potentially other autoimmune diseases. Limited evidence is also present for the association between endometriosis and cardiovascular disease and related conditions (e.g,. hypertension, hypercholesterolemia). A potential explanation for a portion of the increased risk of chronic diseases among women with endometriosis may relate to treatments for endometriosis impacting these outcomes.

Summary: Given the prevalence of endometriosis, understanding the relation between endometriosis and other chronic diseases has the potential to impact the health of many women. However, few high-quality studies with limited biases and adequate follow-up currently exist. Future multi-disciplinary research in prospective cohorts, with ample follow-up time, and detailed information on endometriosis characteristics and treatment is critical to advancing our understanding of this disease and its consequences.

查看原文本刊更多论文

子宫内膜异位症的长期健康后果-途径和治疗调解。

综述目的:本综述的目的是讨论子宫内膜异位症与慢性疾病风险的最新研究，强调子宫内膜异位症的治疗在这些关联中可能发挥的作用。最近的发现:先前的研究表明子宫内膜异位症与上皮性卵巢癌的风险之间存在一致的联系，但与其他癌症的联系尚不清楚。目前的研究表明，子宫内膜异位症可能与系统性红斑狼疮和其他潜在的自身免疫性疾病的风险有关。关于子宫内膜异位症与心血管疾病及相关疾病(如:高血压、高胆固醇血症)。子宫内膜异位症女性患慢性疾病风险增加的部分原因可能与子宫内膜异位症的治疗影响这些结果有关。摘要:鉴于子宫内膜异位症的普遍存在，了解子宫内膜异位症与其他慢性疾病之间的关系可能会影响许多女性的健康。然而，目前很少有高质量的研究具有有限的偏倚和充分的随访。未来多学科的前瞻性队列研究，充足的随访时间，以及子宫内膜异位症特征和治疗的详细信息，对于提高我们对这种疾病及其后果的理解至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Obstetrics and Gynecology Reports OBSTETRICS & GYNECOLOGY-

自引率

0.00%

发文量

期刊介绍： This journal aims to provide expert review articles on significant recent developments in obstetrics and gynecology. Presented in clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the diagnosis, treatment, management, and prevention of conditions that compromise the health of women. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as endometriosis, infertility, menopause, prenatal medicine, and vulval and cervical lesions. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of nearly 20 international members reviews the annual table of contents, suggests articles of special importance to their country/region, and ensures that topics include emerging research. Commentaries from well-known figures in the field are also provided.