RETRACTED: Effects of Methyl Donors on L-Tryptophan Fermentation.

IF 4.2 4区 生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Bioengineered Pub Date : 2026-12-31 Epub Date: 2021-01-31 DOI:10.1080/21655979.2021.1882821
Xiaocui Liu
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引用次数: 0

Abstract

We, the Editor and Publisher of Bioengineered have retracted the following article: Xiaocui Liu, "Effects of Methyl Donors on L-Tryptophan Fermentation," Bioengineered, 10.1080/21655979.2021.1882821.This author became unresponsive after the posting of the author's accepted manuscript version of this article and has not responded to follow up emails for over one year. Since the author has not signed the copyright agreement, Bioengineered cannot proceed with final publication and must remove the accepted author manuscript version from the website.We have been informed in our decision-making by our policy on publishing ethics and integrityandthe COPE guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as "Retracted".

甲基供体对 L-色氨酸发酵的影响
甲基供体是一类向甲基受体提供甲基的化合物,对细胞的功能、生长和增殖起着重要作用;然而,细胞中的甲基供体含量不足以满足细胞的正常需要。在用大肠杆菌生产 L-色氨酸的过程中,由于外源质粒的存在抑制了大肠杆菌的生长,降低了外源基因的表达效率,导致大肠杆菌细胞的生长和产酸能力较弱。因此,我们研究了甲基供体对 L-色氨酸生产的影响。在测试的甲基供体中,氯化胆碱对促进发酵的效果最显著,其次是蛋氨酸。最佳添加方法是在培养基中添加 1.5 克/升蛋氨酸,同时持续添加含 1 克/升氯化胆碱的葡萄糖溶液。最终色氨酸滴度达到 53.5 克/升;细菌的最高生物量达到 51.8 克/升;主要副产物醋酸降至 2.23 克/升,对发酵结果产生了显著影响。
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来源期刊
Bioengineered
Bioengineered BIOTECHNOLOGY & APPLIED MICROBIOLOGY-
CiteScore
8.20
自引率
28.60%
发文量
1114
审稿时长
17 weeks
期刊介绍: Bioengineered provides a platform for publishing high quality research on any aspect of genetic engineering which involves the generation of recombinant strains (both prokaryote and eukaryote) for beneficial applications in food, medicine, industry, environment and bio-defense.
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