Paul D. Stein MD , Afzal Beemath MD , Ronald E. Olson PhD
{"title":"Obesity as a risk factor in venous thromboembolism","authors":"Paul D. Stein MD , Afzal Beemath MD , Ronald E. Olson PhD","doi":"10.1016/j.amjmed.2005.03.012","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><p><span>Whether obesity is an independent risk factor for pulmonary embolism or </span>deep venous thrombosis has not been fully determined.</p></div><div><h3>Methods</h3><p><span>We used the database of the National Hospital Discharge Survey to further investigate the potential risk of obesity in venous </span>thromboembolic disease.</p></div><div><h3>Results</h3><p>The relative risk of deep venous thrombosis, comparing obese patients with non-obese patients, was 2.50 (95% confidence interval [CI] = 2.49-2.51). The relative risk of pulmonary embolism was 2.21 (95% CI = 2.20-2.23). Obese females had a greater relative risk for deep venous thrombosis than obese males, 2.75 (95% CI = 2.74-2.76) versus 2.02 (95% CI = 2.01-2.04). Obesity had the greatest impact on both men and women aged less than 40 years.</p></div><div><h3>Conclusion</h3><p>The data indicate that obesity is a risk factor for venous thromboembolic disease in men as well as women.</p></div>","PeriodicalId":50807,"journal":{"name":"American Journal of Medicine","volume":"118 9","pages":"Pages 978-980"},"PeriodicalIF":5.3000,"publicationDate":"2005-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.amjmed.2005.03.012","citationCount":"550","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S000293430500207X","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 550
Abstract
Purpose
Whether obesity is an independent risk factor for pulmonary embolism or deep venous thrombosis has not been fully determined.
Methods
We used the database of the National Hospital Discharge Survey to further investigate the potential risk of obesity in venous thromboembolic disease.
Results
The relative risk of deep venous thrombosis, comparing obese patients with non-obese patients, was 2.50 (95% confidence interval [CI] = 2.49-2.51). The relative risk of pulmonary embolism was 2.21 (95% CI = 2.20-2.23). Obese females had a greater relative risk for deep venous thrombosis than obese males, 2.75 (95% CI = 2.74-2.76) versus 2.02 (95% CI = 2.01-2.04). Obesity had the greatest impact on both men and women aged less than 40 years.
Conclusion
The data indicate that obesity is a risk factor for venous thromboembolic disease in men as well as women.
期刊介绍:
The American Journal of Medicine - "The Green Journal" - publishes original clinical research of interest to physicians in internal medicine, both in academia and community-based practice. AJM is the official journal of the Alliance for Academic Internal Medicine, a prestigious group comprising internal medicine department chairs at more than 125 medical schools across the U.S. Each issue carries useful reviews as well as seminal articles of immediate interest to the practicing physician, including peer-reviewed, original scientific studies that have direct clinical significance and position papers on health care issues, medical education, and public policy.