Albino Barraza-Villarreal, Paulina Farías, Vicente Díaz Sánchez, Janice L Bailey, Tiaan De Jager, Pierre Ayotte, Mauricio Hernández-Avila, Eric Dewailly
{"title":"Nonoccupational determinants of plasma DDT and p,p'-DDE in men from Chiapas, Mexico.","authors":"Albino Barraza-Villarreal, Paulina Farías, Vicente Díaz Sánchez, Janice L Bailey, Tiaan De Jager, Pierre Ayotte, Mauricio Hernández-Avila, Eric Dewailly","doi":"10.3200/AEOH.59.1.42-49","DOIUrl":null,"url":null,"abstract":"A cross-sectional study was conducted to evaluate nonoccupational biological exposure to 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) compounds and to identify the main factors associated with such exposure in a malaria endemic region in Mexico. Capillary gas column chromatography was used to determine levels of p,p'-DDT and its metabolites in plasma. The mean age of the 144 male participants was 28 yr. Mean p,p'-DDE (1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene) and p,p'-DDT levels were 203.5 μg/l and 67.4 μg/l, respectively. Those whose houses had been sprayed for malaria control had much higher p,p'-DDE levels (p < 0.001). High levels of chlorinated pesticides were found despite being banned in Mexico for agricultural and public health use. Findings demonstrate the role of antimalarial campaigns as a major contributing factor for high DDT plasma levels.","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 1","pages":"42-9"},"PeriodicalIF":0.0000,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3200/AEOH.59.1.42-49","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of environmental health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3200/AEOH.59.1.42-49","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
A cross-sectional study was conducted to evaluate nonoccupational biological exposure to 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) compounds and to identify the main factors associated with such exposure in a malaria endemic region in Mexico. Capillary gas column chromatography was used to determine levels of p,p'-DDT and its metabolites in plasma. The mean age of the 144 male participants was 28 yr. Mean p,p'-DDE (1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene) and p,p'-DDT levels were 203.5 μg/l and 67.4 μg/l, respectively. Those whose houses had been sprayed for malaria control had much higher p,p'-DDE levels (p < 0.001). High levels of chlorinated pesticides were found despite being banned in Mexico for agricultural and public health use. Findings demonstrate the role of antimalarial campaigns as a major contributing factor for high DDT plasma levels.
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