Evaluation of Binax NOW RSV as an acute point-of-care screening test in a paediatric accident and emergency unit.

P L Mackie, E M McCormick, C Williams
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Abstract

Point-of-care tests (POCTs) for respiratory syncytial virus infections are a useful adjunct to reduce the risk of healthcare-associated infections in paediatric wards. A new test based on immunochromatography, Binax NOW RSV, was introduced in the winter of 2002-03. It has user friendly features making it particularly suitable for non-laboratory personnel in a paediatric accident and emergency unit. A prospective study comparing the POCT with laboratory-based direct immunofluorescence (DIF) showed sensitivity of 87% specificity of 94%, positive predictive value of 89% and negative predictive value 92%. The simplicity of Binax NOW RSV should not detract from training staff and maintaining consistent vigilance on quality control.

Binax NOW RSV作为儿科急症室急性护理点筛查试验的评价
呼吸道合胞病毒感染的即时检测(POCTs)是降低儿科病房医疗相关感染风险的有用辅助手段。一种基于免疫层析的新检测方法Binax NOW RSV于2002-03年冬季问世。它具有用户友好的特点,使其特别适用于儿科事故和急诊部门的非实验室人员。一项前瞻性研究将POCT与实验室直接免疫荧光(DIF)进行比较,结果显示敏感性为87%,特异性为94%,阳性预测值为89%,阴性预测值为92%。Binax NOW RSV的简单性不应影响对员工的培训和对质量控制的持续警惕。
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