Carcinoma of the esophagus with mixed basaloid squamous and glandular differentiation: a distinct histological presentation.

Vishal Bhagat, Milind Javle, Joseph Geradts
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引用次数: 3

Abstract

Esophageal cancer is the third most common gastrointestinal cancer and ranks among the ten commonest cancers worldwide. Histologically, approx 60% of esophageal cancers are adenocarcinomas and 40% are squamous cell carcinomas (SCC). Other rare cancers of the esophagus include small-cell carcinomas, squamous cell carcinomas with sarcomatous features, adenoid cystic carcinomas, and mucoepidermoid carcinomas. Basaloid squamous cell carcinoma (BSCC) or basaloid squamous carcinoma (BSC) is a distinct clinicopathological entity, seen more frequently in elderly males. Stage at presentation is often advanced and regional adenopathy or distant metastases are not uncommon at presentation. We describe an unusual case report of esophageal BSCC with glandular differentiation. The clinical significance of glandular differentiation in this rare type of tumor is not known.

食管癌伴基底细胞样、鳞状和腺状混合分化:一种独特的组织学表现。
食管癌是第三大最常见的胃肠道癌症,也是全球十大最常见的癌症之一。组织学上,大约60%的食管癌为腺癌,40%为鳞状细胞癌(SCC)。其他罕见的食道癌包括小细胞癌、具有肉瘤特征的鳞状细胞癌、腺样囊性癌和粘液表皮样癌。基底样鳞状细胞癌(BSCC)或基底样鳞状细胞癌(BSC)是一种独特的临床病理实体,常见于老年男性。表现的阶段通常是晚期,区域性淋巴结病变或远处转移并不罕见。我们报告一例罕见的食管BSCC伴腺分化。这种罕见肿瘤的腺分化的临床意义尚不清楚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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