[Effects of long-term exposure to street traffic exhaust on the development of skin and respiratory tract diseases in children].

Hartmut Ising, Henning Lange-Asschenfeldt, Gert-Friedhelm Lieber, Hubertus Weinhold, Manfred Eilts
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Abstract

The pathogenesis of allergies can be stimulated by adjuvant effects--i.e. air pollutants such as NOx and particles from diesel engines as well as noise--the latter especially during night-time. During sleep, noise signals which are associated with danger (i.e. lorry noise) have the potential to trigger stress reactions even if the noise level is low. Increases of cortisol in the first half of the night seem to play an important role.--In a blind interview study, the combined effects of chronic exposure to traffic related air pollution and noise, upon the risk of skin and respiratory diseases in children were studied. All children between 5-12 years, who had consulted one of two participating pediatricians were included in the study. The pediatricians' diagnoses of 400 children were analysed together with their parents answers on the density of road traffic on their street and several confounding factors. Multiple regression analyses resulted in relative risks of asthma, chronic bronchitis and neurodermitis, which increased significantly with increasing traffic load. A comparison with the literature on such effects caused by air pollution alone, showed that traffic noise during the night might have an adjuvant effect on the pathogenesis of the mentioned diseases.

[长期接触街道交通废气对儿童皮肤和呼吸道疾病发展的影响]。
过敏的发病机制可由辅助作用刺激,即:空气污染物,如氮氧化物和柴油发动机的颗粒,以及噪音——后者尤其是在夜间。在睡眠期间,与危险有关的噪音信号(如卡车噪音)有可能引发压力反应,即使噪音水平很低。前半夜皮质醇的升高似乎起着重要作用。——在一项盲访研究中,研究了长期暴露于与交通有关的空气污染和噪音对儿童皮肤和呼吸系统疾病风险的综合影响。所有5-12岁的儿童,只要咨询过两位参与研究的儿科医生中的一位,都被纳入了研究。分析了400名儿童的儿科医生诊断,以及他们父母对街道上道路交通密度和几个混杂因素的回答。多元回归分析结果显示,哮喘、慢性支气管炎和神经性皮炎的相对风险随着交通负荷的增加而显著增加。与单纯空气污染对上述疾病影响的文献比较表明,夜间交通噪声可能对上述疾病的发病有辅助作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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