The purification and characterization of a new active immunizing polysaccharide prepared from Staphylococcus aureus

Abstract

A new acidic polysaccharide which produces an immunogenic response in mice, dogs and man has been obtained in pure form from acid hydrolysates of Staphylococcus aureus cells. Structural studies show the antigen to be composed of d-glucosaminuronic acid and l-alanine with O- and N-acetyl substitution.