Nonredundant gap junction functions.

Thomas W White
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引用次数: 57

Abstract

The need for molecular heterogeneity of gap junction channel proteins in vivo has been enigmatic. Recently, functional replacement of one channel gene with another in mice and flies has revealed that cellular health depends not simply on gap junction communication but also requires the correct type of intercellular channel subunit.

非冗余间隙连接函数。
体内对间隙连接通道蛋白分子异质性的需要一直是谜。最近,在小鼠和果蝇中,一个通道基因与另一个通道基因的功能替换表明,细胞健康不仅取决于间隙连接的通信,还需要正确类型的细胞间通道亚基。
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