[Value of quantitative IgE measurement].

Allergie et immunologie Pub Date : 2002-12-01
A Sabbah, C Barthet, P Lewin
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Abstract

The results of assay of IgE can only be expressed by a very imprecise system of classes. Quantification of the measurement of IgE by the method of the CAP-system of prognosis of allergic patients. Expression of IgE by a measurement of intensity of fluorescence allows the establishment of a decent curve for each allergen. It makes a method of predictive evaluation of risk of the allergy pathology for each allergen. It significantly improves the sensitivity, since it allows detection of IgE at levels less than 0.35 KUA/l. Thus it gives a considerable improvement for the clinician at the level of diagnosis avoiding the "gold standard" provocation test in allergy diagnosis as well at the level of prognosis.

【IgE定量测定值】。
IgE的检测结果只能通过一个非常不精确的分类系统来表达。过敏患者预后CAP-system法测定IgE的定量研究。通过测量荧光强度来表达IgE,可以为每个过敏原建立一个合适的曲线。提出了对各过敏原的变态反应病理风险进行预测评估的方法。它显著提高了灵敏度,因为它可以在低于0.35 KUA/l的水平下检测IgE。因此,避免了“金标准”激发试验在过敏诊断和预后水平上的应用,对临床医生在诊断水平上有了很大的提高。
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