Early-Onset Periodontitis

Maurizio S. Tonetti Dr., Andrea Mombelli
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引用次数: 355

Abstract

In 1993, the 1st European Workshop on Periodontology explicitly recognized that there was insufficient knowledge to differentiate truly different forms of periodontal disease from differences in the presentation/severity of the same disease. In spite of recent progress in our understanding of periodontal diseases, the issue is far from having been resolved. Classification of periodontal diseases, therefore, remains based upon the definition of specific clinical syndromes. Early-onset periodontitis (EOP) is one such syndrome and comprises a group of pathological conditions leading to loss of periodontal tissues early in life. The notion that classifies periodontitis syndromes as “early-onset” or “adult” is primarily epidemiological in nature and is based on the observation that periodontitis is rather infrequent in children and young adults. Nevertheless, considerable epidemiological evidence indicates that periodontitis does affect children and young adults to a level of severity that may lead to premature exfoliation of primary and/or permanent teeth. Clinical presentation of periodontitis early in the life of an individual is thought to indicate that the etiologic agents have been able to cause considerable tissue damage over a relatively short period of time. It also implies either infection with highly virulent bacteria and/or a highly susceptible subject. The purpose of this review is to discuss the criteria generally utilized to classify EOP, provide the rationale to designate EOP as a distinct disease entity, and to review the evidence justifying a subclassification into particular subgroups of EOP. Ann Periodontol 1999;4:39-52.

早发性牙周炎
1993年,第一届欧洲牙周病研讨会明确认识到,没有足够的知识来区分真正不同形式的牙周病和同一疾病的表现/严重程度的差异。尽管最近我们对牙周病的了解有所进展,但这个问题远未得到解决。因此,牙周病的分类仍然以特定临床综合征的定义为基础。早发性牙周炎(EOP)就是这样一种综合征,它包括一组导致牙周组织在生命早期丧失的病理状况。将牙周炎综合征分类为“早发性”或“成年性”的概念主要是基于流行病学性质,并基于观察到牙周炎在儿童和年轻人中相当罕见。然而,相当多的流行病学证据表明,牙周炎确实会影响儿童和年轻人,其严重程度可能导致乳牙和/或恒牙过早脱落。个体生命早期牙周炎的临床表现被认为表明病原学因素已经能够在相对较短的时间内引起相当大的组织损伤。它还意味着感染了高毒力细菌和/或高度易感的受试者。本综述的目的是讨论通常用于EOP分类的标准,提供将EOP指定为独特疾病实体的理由,并回顾证明EOP细分为特定亚组的证据。牙周病杂志1999;4:39-52。
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