Margaret I Johnston PhD (Associate Director for Vaccine and Prevention Research, Division of AIDS; Assistant Director for AIDS Vaccines)
{"title":"The role of nonhuman primate models in AIDS vaccine development","authors":"Margaret I Johnston PhD (Associate Director for Vaccine and Prevention Research, Division of AIDS; Assistant Director for AIDS Vaccines)","doi":"10.1016/S1357-4310(00)01724-X","DOIUrl":null,"url":null,"abstract":"<div><p>Although animal models have been useful in guiding vaccine development, HIV/AIDS models have not yielded a clear correlate of immunity nor given consistent results on the potential efficacy of various vaccine approaches. Further development and improved uniformity in the use of animal models would maximize their potential to meet the urgent worldwide need for a safe and effective HIV vaccine.</p></div>","PeriodicalId":79448,"journal":{"name":"Molecular medicine today","volume":"6 7","pages":"Pages 267-270"},"PeriodicalIF":0.0000,"publicationDate":"2000-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1357-4310(00)01724-X","citationCount":"37","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular medicine today","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S135743100001724X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 37
Abstract
Although animal models have been useful in guiding vaccine development, HIV/AIDS models have not yielded a clear correlate of immunity nor given consistent results on the potential efficacy of various vaccine approaches. Further development and improved uniformity in the use of animal models would maximize their potential to meet the urgent worldwide need for a safe and effective HIV vaccine.
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