Occurrence of vancomycin-resistant enterococci in relation to the administration of glycopeptide antibiotics.

M Kolár, I Vágnerová, T Látal, I Kohnová
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引用次数: 0

Abstract

Occurrence of vancomycin-resistant enterococci and its relationship to the administration of glycopeptide antibiotics (vancomycin, teicoplanin) was described. A total number of 628 strains of the genus Enterococcus was isolated in the Hemato-oncologic Department of the University Hospital in Olomouc in 1997. Seven strains (1.1%) were found to be resistant to vancomycin. Five of them were identified as Enterococcus faecalis of phenotype VanB, and two strains as E. faecium of phenotype VanA. The administration of vancomycin and teicoplanin in the Hemato-oncologic Department amounted to 85.7% and 89.2%, respectively, of the total consumption of these drugs at the University Hospital.

耐万古霉素肠球菌的发生与糖肽类抗生素的使用有关。
本文描述了耐万古霉素肠球菌的发生及其与糖肽类抗生素(万古霉素、替柯普兰)使用的关系。1997年在奥洛穆茨大学医院血液肿瘤科共分离出628株肠球菌属细菌。7株(1.1%)对万古霉素耐药。其中5株为VanB表型的粪肠球菌,2株为VanA表型的粪肠球菌。万古霉素和替柯planin在血液科的使用分别占大学医院这类药物总使用量的85.7%和89.2%。
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