Application of isothermal microcalorimetry in solid state drug development

Abstract

Microcalorimetry is an analytical technique that has found numerous applications within the pharmaceutical environment. In the realm of pharmaceutics, especially solid state pharmaceutics, the technique has proved to be an invaluable tool. This review addresses the solid state applications of microcalorimetry within the pharmaceutical industry, with a specific focus on stability, compatibility and amorphicity determinations.