[Fas/Fas ligand mRNA are expressed in Helicobacter pylori infected mucosa].

Abstract

Helicobacter pylori (Hp) seems to possess an inflammatory as well as immun-modulatory potential. The investigation revealed that both Fas and FasLigand are expressed in the gastric mucosa independently of the Hp infection status and with no significant difference to the expression profile in PBMC. In conclusion, Fas-FasLigand interaction could play a role in immune regulation of Hp gastritis and induction or mediation of epithelial injury.