Osseous manifestation of Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy). A case report and review of the literature.

Abstract

Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is an unusual form of histiocytic disorder. Bone lesions are infrequent. We describe a 33-year-old man with involvement of multiple bones but without lymphadenopathy at the time of presentation. The literature on osseous manifestation in this condition is reviewed.