{"title":"[The cell cycle patterns of the hemopoietic cells under the action of ionizing radiation].","authors":"D A Shmarov, G I Kozinets","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The analysis of changes in bone marrow cell cycle induced by ionising radiation in animals and humans in comparison with myelogram evidence on postradiation death of myelocaryocytes shows that radiation is responsible for pronounced dose-dependent shifts in cell cycle early after radiation prior to postradiation cell death. These phenomena are considered in light of new hypophysis on the existence of cell cycle regulation system and initiation of apoptosis at the cell level.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 6","pages":"25-9"},"PeriodicalIF":0.2000,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gematologiya I Transfuziologiya","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"HEMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The analysis of changes in bone marrow cell cycle induced by ionising radiation in animals and humans in comparison with myelogram evidence on postradiation death of myelocaryocytes shows that radiation is responsible for pronounced dose-dependent shifts in cell cycle early after radiation prior to postradiation cell death. These phenomena are considered in light of new hypophysis on the existence of cell cycle regulation system and initiation of apoptosis at the cell level.
期刊介绍:
The journal publishes original theoretical and clinical studies, lectures, reviews, and practical notes concerning various problems of hematology and clinical and industrial transfusion. The journal provides information on the etiology, pathogenesis, diagnosis and treatment of blood disorders as well as on related non-hematological conditions (internal diseases, poisoning, exposure to ionizing radiation etc.).