[The cell cycle patterns of the hemopoietic cells under the action of ionizing radiation].

IF 0.2 4区 医学 Q4 HEMATOLOGY
Gematologiya I Transfuziologiya Pub Date : 1995-11-01
D A Shmarov, G I Kozinets
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引用次数: 0

Abstract

The analysis of changes in bone marrow cell cycle induced by ionising radiation in animals and humans in comparison with myelogram evidence on postradiation death of myelocaryocytes shows that radiation is responsible for pronounced dose-dependent shifts in cell cycle early after radiation prior to postradiation cell death. These phenomena are considered in light of new hypophysis on the existence of cell cycle regulation system and initiation of apoptosis at the cell level.

[电离辐射作用下造血细胞的细胞周期模式]。
对动物和人类电离辐射诱导的骨髓细胞周期变化的分析,与辐射后髓核细胞死亡的骨髓造影证据相比较,表明辐射是导致辐射后细胞死亡前早期细胞周期明显的剂量依赖性变化的原因。这些现象是根据细胞周期调控系统的存在和细胞水平上细胞凋亡的启动而产生的新假说来考虑的。
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来源期刊
CiteScore
0.80
自引率
66.70%
发文量
29
审稿时长
>12 weeks
期刊介绍: The journal publishes original theoretical and clinical studies, lectures, reviews, and practical notes concerning various problems of hematology and clinical and industrial transfusion. The journal provides information on the etiology, pathogenesis, diagnosis and treatment of blood disorders as well as on related non-hematological conditions (internal diseases, poisoning, exposure to ionizing radiation etc.).
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