Epidemiology of psychiatric disorders in Edmonton. Panic disorder.

C L Dick, R C Bland, S C Newman
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Abstract

A random sample of 3258 adult household residents of Edmonton, Alberta, Canada were interviewed by trained lay interviewers using the Diagnostic Interview Schedule (DIS), which gives DSM-III diagnostic data on each individual interviewed. This paper reports results for panic disorder. Panic disorder was found to affect women primarily (female:male morbidity risk 2.2:1). The mean age of onset (first symptom) was 19.3 years for men and 21.5 years for women. Rarely did symptoms first occur after the age of forty. The lifetime prevalence rate was 1.7% for women and 0.8% for men and the lifetime morbidity risk was 3.7% for females and 1.7% for males. All twelve panic symptoms were found to be highly specific for panic disorder. Women complained of more (means = 8.0) symptoms than men (means = 6.0). On average 7.3 symptoms were reported. Those with panic disorder showed increased lifetime prevalence rates for major depressive episode (73.4%), alcohol abuse/dependence (54.2%), drug abuse/dependence (43%) and phobia (44.2%). Altogether, 90.4% of those with panic disorder also met criteria for another DSM-III diagnosis, which was 2.7 times the rate in those who did not have panic disorder.

埃德蒙顿精神疾病流行病学。恐慌症。
随机抽取3258名加拿大艾伯塔省埃德蒙顿的成年家庭居民,由训练有素的非专业采访者使用诊断访谈表(DIS)进行访谈,该访谈表提供了每位受访者的DSM-III诊断数据。本文报道了惊恐障碍的结果。惊恐障碍主要影响女性(女性:男性发病风险2.2:1)。男性平均发病年龄(首次症状)为19.3岁,女性为21.5岁。很少在40岁以后才出现症状。女性的终生患病率为1.7%,男性为0.8%,女性的终生发病率为3.7%,男性为1.7%。所有12种恐慌症状都被发现是恐慌障碍的高度特异性。女性抱怨的症状(平均值= 8.0)多于男性(平均值= 6.0)。平均报告7.3种症状。惊恐障碍患者在重度抑郁发作(73.4%)、酒精滥用/依赖(54.2%)、药物滥用/依赖(43%)和恐惧症(44.2%)方面的终生患病率均有所增加。总的来说,90.4%的恐慌症患者也符合另一种DSM-III诊断标准,这是没有恐慌症患者的2.7倍。
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