Thresholds and mechanisms of retinal damage from a white-light laser.

Abstract

Rhesus monkey retinae* were exposed to single 300-nsec pulses of light from a new dye-laser system, which produces a white-light effect by the simultaneous, coaxial generation of 480-, 508-, 528and 595-nm wavelengths. EDso values (i.e. the dose that has a 50% probability of producing minimum ophthalmoscopically visible damage) for 1and 24-hr post exposure examinations were, respectively, 3.9 and 2.7 pJ total intraocular energy. These EDso values are similar to single-wavelength exposures of comparable pulse duration.