Fluid kinetics during hemodialysis.

Abstract

The reflection coefficient of urea was estimated in the present paper since some clinical experiences suggest an importance of urea dependent osmolality for the circulatory stability. In the physiology, the reflection coefficient of urea is usually regarded to be negligibly small though it varies from one organ to another. The value obtained in the present paper is large and urea was supposed osmotically to be active affecting the fluid movement across the capillary wall. A fall of urea concentration during hemodialysis may aggravate potentially the decrease of circulating blood volume.