{"title":"Comparisons between the abilities of various human and ovine plasmas to inhibit prostaglandin synthesis","authors":"M.D. Mitchell , S.P. Brennecke , P.A. Denning-Kendall , W.J. McDonald Gibson , S.A. Saeed , H.O.J. Collier","doi":"10.1016/0161-4630(81)90108-7","DOIUrl":null,"url":null,"abstract":"<div><p>The ability of various human and ovine blood plasmas to inhibit prostaglandin synthesis <span><math><mtext>in vitro</mtext></math></span> has been tested. Human plasmas were significantly more potent in their ability to inhibit prostaglandin synthesis than their counterpart ovine plasmas. In general, female plasma had greater inhibitory activities than male plasmas and adult plasmas were more active than fetal plasmas. There was no simple correlation between the activity of plasmas as inhibitors of prostaglandin synthesis and their respective albumin or haptoglobin contents.</p></div>","PeriodicalId":76381,"journal":{"name":"Prostaglandins and medicine","volume":"6 5","pages":"Pages 495-501"},"PeriodicalIF":0.0000,"publicationDate":"1981-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0161-4630(81)90108-7","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Prostaglandins and medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0161463081901087","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
The ability of various human and ovine blood plasmas to inhibit prostaglandin synthesis has been tested. Human plasmas were significantly more potent in their ability to inhibit prostaglandin synthesis than their counterpart ovine plasmas. In general, female plasma had greater inhibitory activities than male plasmas and adult plasmas were more active than fetal plasmas. There was no simple correlation between the activity of plasmas as inhibitors of prostaglandin synthesis and their respective albumin or haptoglobin contents.