Use of serial carcinoembryonic antigen assays in detecting relapses in breast cancer involving high risk of metastasis

European Journal of Cancer (1965) Pub Date : 1981-02-01 DOI:10.1016/0014-2964(81)90041-4

J.F. Chatal, F. Chupin, G. Ricolleau, J.L. Tellier, A. Le Mevel, P. Fumoleau, O. Godin, B.P. Le Mevel

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引用次数: 26

Abstract

Serial CEA assays on serum using the direct radioimmunoassay method (Marcoule, France) were performed on 76 breast cancer patients with node involvement or rapid local development of tumors who were undergoing chemotherapy. The patients were followed up for a mean period of 28 months, and assays were repeated every 2.5 months on average. Out of 521 assays performed on 49 patients who remained in complete remission, there were 37 instances of significant, but transitory, rise in CEA level which, in 8 cases, could be attributed to intercurrent benign inflammation. In 15 out of 27 patients who had relapses, there was a significant and persistent rise in CEA level which, in 11 cases, preceded clinical signs by 6 months on average. In the 12 other cases, CEA level remained constant and normal despite relapse.

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使用系列癌胚抗原检测乳腺癌复发的高风险转移

使用直接放射免疫分析法(Marcoule, France)对76例接受化疗的淋巴结受累或肿瘤局部快速发展的乳腺癌患者进行了血清CEA系列检测。患者平均随访28个月，平均每2.5个月复查一次。在对49例完全缓解的患者进行的521项检测中，有37例CEA水平显著但短暂上升，其中8例可归因于并发良性炎症。在27例复发患者中，有15例CEA水平显著且持续上升，其中11例比临床症状平均早6个月。在其他12例中，CEA水平保持稳定，尽管复发。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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European Journal of Cancer (1965)

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