Chorioallantoic membrane grafting of the embryonic murine kidney. An improved in vitro technique for studying kidney morphogenesis.

Abstract

Previous experimental investigations of embryonic kidney development with in vitro organ culture techniques have been limited by the short duration of explant viability. Utilization of chick chorioallantoic membranes for transplanting undifferentiated murine kidney rudiments has allowed vascularization of the grafts with advanced maturation and the appearance of early nephron units.