{"title":"Red blood cell susceptibility to hydrogen peroxide (H2O2) lysis in chronic hemodialysis patients.","authors":"R K Albright, R P White","doi":"10.3109/08860228209049855","DOIUrl":null,"url":null,"abstract":"<p><p>To assess susceptibility to oxidant induced membrane damage, the red blood cell H2O2 hemolysis test was performed in fifty-three chronic hemodialysis patients. Uremic red blood cells were not more susceptible to 2.5% H2O2 lysis pre or postdialysis than were control red blood cells. Oxidant induced red blood cell lysis is a function of the strength of the oxidant and not a testable intrinsic defect of the uremic red blood cell.</p>","PeriodicalId":79208,"journal":{"name":"Clinical and experimental dialysis and apheresis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860228209049855","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and experimental dialysis and apheresis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/08860228209049855","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
To assess susceptibility to oxidant induced membrane damage, the red blood cell H2O2 hemolysis test was performed in fifty-three chronic hemodialysis patients. Uremic red blood cells were not more susceptible to 2.5% H2O2 lysis pre or postdialysis than were control red blood cells. Oxidant induced red blood cell lysis is a function of the strength of the oxidant and not a testable intrinsic defect of the uremic red blood cell.