Multi-omics analysis reveals the influence of tetracycline on the growth of ryegrass root

IF 12.2 1区环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL

Journal of Hazardous Materials Pub Date : 2022-08-05 DOI:10.1016/j.jhazmat.2022.129019

Tao Han , Zhaorong Mi , Zhe Chen , Jinjin Zhao , Haiguang Zhang , Yang Lv , Shouyang Du , Ruifang Bu , Junguo Zhou , Xinzheng Li , Zhiqiang Sun , Zhuo Chen , Yiting Song , Jun Zhang , Ruijuan Hao , Shidong Ge

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引用次数: 7

Abstract

Environmental factors, including antibiotics such as tetracycline, can alter biological processes in plants. To ascertain how cell/tissue response to tetracycline, a multi-omic analysis was implemented to explore the molecular mechanism of tetracycline influencing the growth of ryegrass root. Tetracycline induced extensive changes in the root metabolome in plants, particularly impacting metabolites of flavonoid metabolic pathways, which were supported through consistent differences between transcriptome and proteome. Cross-comparison between mRNA and protein contents considered the authentication of congruence with related metabolites and revealed changes of several biological processes under tetracycline stress. Overall, we present an undemanding multi-omic strategy to survey the significant influence on the root under tetracycline stress.

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多组学分析揭示了四环素对黑麦草根系生长的影响

环境因素，包括四环素等抗生素，可以改变植物的生物过程。为了了解细胞/组织对四环素的反应，我们采用多组学方法探讨了四环素影响黑麦草根生长的分子机制。四环素诱导了植物根代谢组的广泛变化，特别是对类黄酮代谢途径的代谢物的影响，这一点通过转录组和蛋白质组之间的一致差异得到了支持。mRNA和蛋白含量的交叉比较考虑了与相关代谢物的一致性验证，揭示了四环素胁迫下一些生物过程的变化。总的来说，我们提出了一个简单的多组学策略来调查四环素胁迫对根的显著影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Hazardous Materials 工程技术-工程：环境

CiteScore

25.40

自引率

5.90%

发文量

3059

审稿时长

58 days

期刊介绍： The Journal of Hazardous Materials serves as a global platform for promoting cutting-edge research in the field of Environmental Science and Engineering. Our publication features a wide range of articles, including full-length research papers, review articles, and perspectives, with the aim of enhancing our understanding of the dangers and risks associated with various materials concerning public health and the environment. It is important to note that the term "environmental contaminants" refers specifically to substances that pose hazardous effects through contamination, while excluding those that do not have such impacts on the environment or human health. Moreover, we emphasize the distinction between wastes and hazardous materials in order to provide further clarity on the scope of the journal. We have a keen interest in exploring specific compounds and microbial agents that have adverse effects on the environment.