{"title":"Inhibition and stimulation of rat thymocytes in vitro by partial hepatectomy","authors":"L. Desser-Wiest , H. Desser","doi":"10.1016/S0014-4908(80)80060-3","DOIUrl":null,"url":null,"abstract":"<div><p>Male Sprague Dawley rats were partially hepatectomized. At different times after operation, their thymocytes were isolated and incubated for 5 hours at 37 °C in an RPMI medium with 10% rat control serum and their incorporation of <sup>3</sup>HTdR was then determined. 1 and 2 days after partial hepatectomy, the thymocytes incorporate much less <sup>3</sup>H TdR; from day 3 to day 10 a stimulation of proliferation was observed. Thymocytes of control animals incorporate much less <sup>3</sup>HTdR when incubated with sera from animals 1 day to 4 days post partial hepatectomy. Corticosterone, cortisol, testosterone, α-fetoglobulin, putrescine, sperimidine, spermine and cadaverine do not influence the incorporation of labelled thymidine into control thymocytes during an incubation of 5 hours.</p></div>","PeriodicalId":75841,"journal":{"name":"Experimentelle Pathologie","volume":"18 2","pages":"Pages 114-117"},"PeriodicalIF":0.0000,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0014-4908(80)80060-3","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimentelle Pathologie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0014490880800603","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2011/11/8 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Male Sprague Dawley rats were partially hepatectomized. At different times after operation, their thymocytes were isolated and incubated for 5 hours at 37 °C in an RPMI medium with 10% rat control serum and their incorporation of 3HTdR was then determined. 1 and 2 days after partial hepatectomy, the thymocytes incorporate much less 3H TdR; from day 3 to day 10 a stimulation of proliferation was observed. Thymocytes of control animals incorporate much less 3HTdR when incubated with sera from animals 1 day to 4 days post partial hepatectomy. Corticosterone, cortisol, testosterone, α-fetoglobulin, putrescine, sperimidine, spermine and cadaverine do not influence the incorporation of labelled thymidine into control thymocytes during an incubation of 5 hours.
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