The proliferation activity of the rat thymocytes after partial hepatectomy

Abstract

The influence of partial hepatectomy, unilateral nephrectomy and shamoperation on thymocyte proliferation capacity in male rats was investigated. The wet weight and the cell number declines significantly after partial hepatectomy. A stimulation of mitotic activity and H³TdR incorporation on day 3 to day 6 was also observed in partially hepatectomized animals. The polyamine content of the thymocytes was transiently decreased 2 days post partial hepatectomy and shamoperation. Thereafter the amine concentrations increased and remained elevated in the case of partially hedatectomized animals. No significant changes in the content of histamine were observed.