[Innervation of islands of Langerhans. Light and electron microscopic studies of the pancreas in laboratory animals].

Abstract

A-, B- and D cells of the pancreas were found to be innervated. Moreover, at one and the same insular cell numerous and extended synapses are formed with very small synaptic clefts (less than 20 nm). It is ultrahistochemically detectable that A- and B cells are likewise sympathetically (adrenergically) innervated. Including specific data from the literature, the insular cell apparatus must be regarded as a organ which is highly controlled by the nervous system.