[Serum factors present in patients with carcinoma of the bladder: effect on cell-mediated immunity].

Abstract

The effect of the sera from patients with bladder carcinoma upon the blastic transformation of T lymphocytes and the antibody-dependent K cell cytotoxicity is studied. The sera from cancer patients inhibits both the T cell blastic transformation and the antibody-dependent K cell cytotoxicity, the effect is attained by a different mechanism, and the degree of inhibition correlates with the histologic malignancy and infiltration.