Effects of cholecystokinin-related peptides on retention of passive avoidance behaviour.

M Fekete, B Penke, G Telegdy
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Abstract

Effects of intraperitoneal administration of cholecystokinin (CCK)-related peptides were studied on retention of single-trial learning passive avoidance behaviour. The COOH-terminal octapeptide of CCK (CCK-1-8-SE), the unsulfated octapeptide (CCK-1-8-NS), as well as the COOH-terminal tetrapeptide of CCK (CCK-5-8), administered immediately after the learning trial, facilitated passive avoidance behaviour. The data indicate that these peptides may influence memory consolidation processes.

胆囊收缩素相关肽对被动回避行为保留的影响。
研究了腹腔注射胆囊收缩素(CCK)相关肽对单次学习被动回避行为保留的影响。在学习试验后立即给药CCK的cooh末端八肽(CCK-1-8- se)、未酸化八肽(CCK-1-8- ns)以及CCK的cooh末端四肽(CCK-5-8),促进了被动回避行为。数据表明,这些肽可能影响记忆巩固过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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