Metabolism of [1-14C] acetate in guinea pigs with chronic vitamin C hyposaturation

Abstract

Oxidation of [1-¹⁴C] acetate to ¹⁴CO₂ and its incorporation into liver cholesterol in guinea pigs was not significantly altered in case of chronic hypovitaminosis C. Conspicuous accumulation of total cholesterol in the liver of guinea pigs with chronic hypovitaminosis C cannot be explained in terms of a change in acetate metabolism.