Nuclear bodies in Hodgkin's disease.

Abstract

Nuclear bodies in Hodgkin's disease were found in four out of twenty-one cases studied under the electron microscope. They were present in histiocytes, vascular endothelial and lymphoid cells. They were found in lymphoic blastoid cells (Hodgkin's cells) but not in Reed Sternberg cells. Their morphology was characterized by two predominant patterns: fibrillar and granular. The current concepts of morphology and pathogensis of these formations are discussed.