A Liquid Metal Route for Designing Stretchability and Nanoporosity in Gold Thin Film Bioelectrodes

IF 9.1 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Nano Letters Pub Date : 2026-11-02 DOI:10.1021/acs.nanolett.6c04290

Lucy Johnston,Jinke Ren,Shuhua Peng,Ming Li,Priyank Kumar,Jianbo Tang

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Abstract

Nanostructured gold thin films are widely used biosensing materials due to their inertness, high surface area, favorable electrochemical properties, antifouling abilities, and biocompatibility. However, the structural integrity of thin films is easily compromised when stretched. Here we present a liquid metal synthesis route that allows room temperature fabrication of nanoscale thickness, nanoporous gold (NPAu) electrodes on stretchable polydimethylsiloxane (PDMS). Carbon nanofibers (CNFs) are introduced to maintain electrical conductivity of NPAu by suppressing crack formation/propagation and establishing intercrack conductive pathways. The PDMS-supported, CNF-reinforced NPAu retains its electrical conductivity at strains up to 80% and a relative resistance change of 11% under 2000 cyclic loads at 20% strain, demonstrating exceptional stability. NPAu-CNF demonstrates an electroactive surface area 1.8 times that of commercial Au electrodes, along with superior antifouling performance. These findings establish a protocol for realizing stretchability in thin film bioelectrodes, meeting the demand for developing conformable yet highly integrated biosensors.

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一种设计金薄膜生物电极可拉伸性和纳米孔隙度的液态金属途径

纳米结构的金薄膜具有惰性、高比表面积、良好的电化学性能、防污能力和生物相容性等优点，是目前广泛应用的生物传感材料。然而，薄膜的结构完整性在拉伸时很容易受到损害。在这里，我们提出了一种液态金属合成路线，允许在室温下在可拉伸聚二甲基硅氧烷（PDMS）上制造纳米级厚度的纳米孔金（NPAu）电极。纳米碳纤维（CNFs）通过抑制裂纹的形成/扩展和建立裂纹间导电通路来维持NPAu的导电性。pdms支持的cnf增强NPAu在应变高达80%时保持其导电性，在20%应变下2000次循环载荷下的相对电阻变化为11%，表现出优异的稳定性。NPAu-CNF的电活性表面积是商用Au电极的1.8倍，同时具有优异的防污性能。这些发现为实现薄膜生物电极的可拉伸性建立了一个协议，满足了开发兼容且高度集成的生物传感器的需求。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nano Letters 工程技术-材料科学：综合

CiteScore

16.80

自引率

2.80%

发文量

1182

审稿时长

1.4 months

期刊介绍： Nano Letters serves as a dynamic platform for promptly disseminating original results in fundamental, applied, and emerging research across all facets of nanoscience and nanotechnology. A pivotal criterion for inclusion within Nano Letters is the convergence of at least two different areas or disciplines, ensuring a rich interdisciplinary scope. The journal is dedicated to fostering exploration in diverse areas, including: - Experimental and theoretical findings on physical, chemical, and biological phenomena at the nanoscale - Synthesis, characterization, and processing of organic, inorganic, polymer, and hybrid nanomaterials through physical, chemical, and biological methodologies - Modeling and simulation of synthetic, assembly, and interaction processes - Realization of integrated nanostructures and nano-engineered devices exhibiting advanced performance - Applications of nanoscale materials in living and environmental systems Nano Letters is committed to advancing and showcasing groundbreaking research that intersects various domains, fostering innovation and collaboration in the ever-evolving field of nanoscience and nanotechnology.