Primary Intratesticular glomus tumor: a rare mesenchymal neoplasm and a diagnostic challenge.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

Oxford Medical Case Reports Pub Date : 2026-10-04 eCollection Date: 2026-10-01 DOI:10.1093/omcr/omag075

Zahra Aminparast, Payam Nikjo, Donya Rahmati, Paria Nikjo

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引用次数: 0

Abstract

Background: Glomus tumors are rare mesenchymal neoplasms of perivascular origin, most commonly found in the dermis or subcutis of distal extremities. Testicular involvement is exceptionally uncommon and poses a diagnostic challenge due to histopathologic similarities with other intratesticular tumors.

Case presentation: We describe an 85-year-old man with a painless, gradually enlarging left testicular mass. Imaging and tumor markers were inconclusive. Radical orchiectomy revealed a well-circumscribed intratesticular lesion. Histology showed uniform round cells with eosinophilic cytoplasm arranged around vascular spaces. Immunohistochemistry demonstrated strong positivity for SMA and negativity for germ cell, stromal, neuroendocrine, and melanocytic markers, confirming the diagnosis of a primary intratesticular glomus tumor.

Conclusion: This case underscores the need to consider rare mesenchymal tumors in the differential diagnosis of testicular masses in elderly patients and highlights the pivotal role of immunohistochemistry in establishing an accurate diagnosis.

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原发性睾丸内血管球瘤：一种罕见的间充质肿瘤和诊断上的挑战。

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来源期刊

Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

125

审稿时长

19 weeks

期刊介绍： Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.