{"title":"Interpreting corneal changes after PRK: Integrating biomechanics with tomographic remodeling.","authors":"Murat Kaşıkcı, Göksu Alaçamlı, Konuralp Yakar","doi":"10.1007/s10103-026-05074-1","DOIUrl":null,"url":null,"abstract":"<p><p>Photorefractive keratectomy (PRK) alters corneal biomechanical and tomographic measurements, but postoperative change, an abnormal index classification, and progressive ectasia are distinct. Saif et al. reported biomechanical changes at 6 months; a separate Pentacam cohort showed tomographic changes at 1 month. Clinically and topographically normal eyes assessed approximately 25 years after PRK also had frequent abnormal classifications. These different cohorts and observation periods cannot establish a common postoperative trajectory or show that an abnormal result is benign in an individual eye. Prospective paired Pentacam and Corvis ST measurements in the same eyes, followed by independent validation, are needed to develop postoperative references. Until then, serial clinical and tomographic findings should inform interpretation of isolated index abnormalities.</p>","PeriodicalId":17978,"journal":{"name":"Lasers in Medical Science","volume":"41 1","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13677635/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lasers in Medical Science","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s10103-026-05074-1","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Photorefractive keratectomy (PRK) alters corneal biomechanical and tomographic measurements, but postoperative change, an abnormal index classification, and progressive ectasia are distinct. Saif et al. reported biomechanical changes at 6 months; a separate Pentacam cohort showed tomographic changes at 1 month. Clinically and topographically normal eyes assessed approximately 25 years after PRK also had frequent abnormal classifications. These different cohorts and observation periods cannot establish a common postoperative trajectory or show that an abnormal result is benign in an individual eye. Prospective paired Pentacam and Corvis ST measurements in the same eyes, followed by independent validation, are needed to develop postoperative references. Until then, serial clinical and tomographic findings should inform interpretation of isolated index abnormalities.
期刊介绍：
Lasers in Medical Science (LIMS) has established itself as the leading international journal in the rapidly expanding field of medical and dental applications of lasers and light. It provides a forum for the publication of papers on the technical, experimental, and clinical aspects of the use of medical lasers, including lasers in surgery, endoscopy, angioplasty, hyperthermia of tumors, and photodynamic therapy. In addition to medical laser applications, LIMS presents high-quality manuscripts on a wide range of dental topics, including aesthetic dentistry, endodontics, orthodontics, and prosthodontics.
The journal publishes articles on the medical and dental applications of novel laser technologies, light delivery systems, sensors to monitor laser effects, basic laser-tissue interactions, and the modeling of laser-tissue interactions. Beyond laser applications, LIMS features articles relating to the use of non-laser light-tissue interactions.
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