Atypical Stafne bone defect: a systematic review.

IF 3.6 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Investigations Pub Date : 2026-10-17 DOI:10.1007/s00784-026-07212-z

Thomas Laidin, Francesca Mangione

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引用次数: 0

Abstract

Objectives: Atypically located Stafne bone defects (SBDs) may be challenging to identify because they deviate from the typical posterior mandibular presentation. This systematic review aims to analyze and synthesize the radiographic, anatomical, and histological characteristics of atypically located SBDs reported in the literature and to assist clinicians in orienting the diagnostic hypothesis.

Materials and methods: A comprehensive literature search was conducted in the PubMed, Scopus, Embase, and Web of Science databases up to January 2026. Eligibility criteria included English-language case reports and case series describing atypically located Stafne bone defects (SBDs). Study selection, data extraction, and quality assessment were performed independently by two reviewers using an adapted assessment tool for case reports.

Results: Seventy studies encompassing 91 atypical cases were included. Atypically located SBDs were most frequently reported in the anterior mandible. Despite their variable localization, these defects share key anatomical and radiographic features with classical SBDs, including well-defined unilocular radiolucencies and lingual cortical depressions. Advanced imaging modalities, particularly cone-beam computed tomography (CBCT) and magnetic resonance imaging (MRI), play an important role in confirming these features and in orienting the diagnostic hypothesis. Histological analysis, when available, most commonly revealed normal salivary gland tissue without evidence of neoplastic transformation.

Conclusions: Atypically located SBDs demonstrate consistent radiographic and anatomical characteristics that may assist clinicians in orienting the diagnostic hypothesis. This review improves the understanding of this under-recognized anatomical variant and highlights the importance of appropriate imaging evaluation in ambiguous cases.

Clinical relevance: Recognition of these features may facilitate accurate diagnosis and help avoid unnecessary invasive procedures.

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非典型性骨缺损：系统回顾。

目的：非典型定位骨缺损（sbd）可能具有挑战性，以确定，因为他们偏离了典型的下颌后表现。本系统综述旨在分析和综合文献中报道的非典型位置sbd的影像学、解剖学和组织学特征，并协助临床医生确定诊断假设。材料和方法：对截至2026年1月的PubMed、Scopus、Embase和Web of Science数据库进行了全面的文献检索。入选标准包括英文病例报告和描述非典型位置骨缺损（sbd）的病例系列。研究选择、数据提取和质量评估由两名审稿人使用一种适用于病例报告的评估工具独立完成。结果：纳入70项研究，包括91例非典型病例。非典型位置的sbd最常报道在前下颌骨。尽管它们的定位不同，但这些缺陷与经典sbd具有关键的解剖学和影像学特征，包括明确的单眼放射率和舌皮质凹陷。先进的成像方式，特别是锥束计算机断层扫描（CBCT）和磁共振成像（MRI），在确认这些特征和确定诊断假设方面发挥了重要作用。组织学分析，当可用时，最常见的是显示正常的唾液腺组织，没有肿瘤转化的证据。结论：非典型定位sbd表现出一致的放射学和解剖学特征，可以帮助临床医生确定诊断假设。这篇综述提高了对这种未被认识的解剖变异的理解，并强调了在模棱两可的病例中适当的影像学评估的重要性。临床相关性：识别这些特征可能有助于准确诊断，并有助于避免不必要的侵入性手术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Oral Investigations 医学-牙科与口腔外科

CiteScore

6.30

自引率

5.90%

发文量

484

审稿时长

3 months

期刊介绍： The journal Clinical Oral Investigations is a multidisciplinary, international forum for publication of research from all fields of oral medicine. The journal publishes original scientific articles and invited reviews which provide up-to-date results of basic and clinical studies in oral and maxillofacial science and medicine. The aim is to clarify the relevance of new results to modern practice, for an international readership. Coverage includes maxillofacial and oral surgery, prosthetics and restorative dentistry, operative dentistry, endodontics, periodontology, orthodontics, dental materials science, clinical trials, epidemiology, pedodontics, oral implant, preventive dentistiry, oral pathology, oral basic sciences and more.