Modifiable Lifestyle Risk Factors for Lower Extremity Arteriosclerosis Obliterans in a High-Risk Population: A Retrospective Case-Control Study.

IF 2.6 4区医学 Q2 HEALTH CARE SCIENCES & SERVICES

Risk Management and Healthcare Policy Pub Date : 2026-10-10 eCollection Date: 2026-01-01 DOI:10.2147/RMHP.S618865

Yuan Bai, Ting Han, Zhuoxia Li, Xin Wu, Ying Yu, Shujin Zhang

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引用次数: 0

Abstract

Objective: To identify specific modifiable lifestyle risk factors associated with lower extremity arteriosclerosis obliterans (LEASO) in a high-risk screening population to guide targeted primary prevention.

Methods: This retrospective case-control study enrolled 300 individuals at high risk for LEASO from a tertiary hospital in Shanxi Province, China. Baseline lifestyle habits were assessed using the Lifestyle and Lower Extremity Vascular Health Questionnaire, and participants were followed for 2 years. Multivariate logistic regression was used to analyze the relationship between lifestyle habits and LEASO incidence.

Results: Multivariate logistic regression identified smoking (OR = 2.289, 95% CI: 1.254-4.178), high-salt diet (OR = 2.040, 95% CI: 1.334-3.120), high-fat diet (OR = 1.988, 95% CI: 1.232-3.239), high-cholesterol diet (OR = 1.571, 95% CI: 1.131-2.183), staying up late (OR = 1.826, 95% CI: 1.119-2.980), and prolonged sitting (OR = 2.259, 95% CI: 1.034-4.937) as significant independent risk factors (all P < 0.05).

Conclusion: In high-risk populations, specific lifestyle factors-particularly smoking, prolonged sitting, and poor dietary habits-are strongly associated with LEASO. These findings highlight the critical need for behavior-targeted community interventions to mitigate peripheral vascular disease progression.

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来源期刊

Risk Management and Healthcare Policy Medicine-Public Health, Environmental and Occupational Health

CiteScore

6.20

自引率

2.90%

发文量

242

审稿时长

16 weeks

期刊介绍： Risk Management and Healthcare Policy is an international, peer-reviewed, open access journal focusing on all aspects of public health, policy and preventative measures to promote good health and improve morbidity and mortality in the population. Specific topics covered in the journal include: Public and community health Policy and law Preventative and predictive healthcare Risk and hazard management Epidemiology, detection and screening Lifestyle and diet modification Vaccination and disease transmission/modification programs Health and safety and occupational health Healthcare services provision Health literacy and education Advertising and promotion of health issues Health economic evaluations and resource management Risk Management and Healthcare Policy focuses on human interventional and observational research. The journal welcomes submitted papers covering original research, clinical and epidemiological studies, reviews and evaluations, guidelines, expert opinion and commentary, and extended reports. Case reports will only be considered if they make a valuable and original contribution to the literature. The journal does not accept study protocols, animal-based or cell line-based studies.