Xiao Wang, Guofang Xu, Chunyou Ye, Yinhao Ren, Xuefei Yu, Jijun Han
{"title":"Effect of frequency-dependent dielectric properties features on the accuracy of cancerous liver tissue identification.","authors":"Xiao Wang, Guofang Xu, Chunyou Ye, Yinhao Ren, Xuefei Yu, Jijun Han","doi":"10.1080/15368378.2026.2748639","DOIUrl":null,"url":null,"abstract":"<p><p>Differences in the dielectric properties of normal and cancer tissues provide invaluable information for distinguishing them. The open-ended coaxial probe technique is a recognized method for measuring the dielectric properties of normal and cancerous tissues. Machine learning is widely used to classify these tissues on the basis of their dielectric properties. However, the current classification technique is error‑prone, as selecting an insufficient number of features may result in diminished accuracy, whereas selecting an excessive number can lead to overfitting in classification models. This study systematically investigated the impact of noise and individual variability, with particular emphasis on how the number of frequency points, which represents the features, influences the accuracy of cancer identification. The K-nearest neighbor (KNN) algorithm was used to analyze the dielectric properties, and the model was generalized to phantoms. Results demonstrate that as the number of frequency points increases, accuracy stabilizes and improves. However, accuracy gradually plateaued and slightly decreased with excessive frequency points, suggesting potential overfitting. A comprehensive analysis recommends using 20 frequency points for accurate tissue identification. When generalized to phantom dielectric properties data, the model misclassified only one phantom. The dielectric properties offer valuable insights into medical diagnostics. The KNN was effective in distinguishing between normal and cancer tissues. This study also provides practical recommendations for cost-effective dielectric properties analysis.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"1-15"},"PeriodicalIF":1.5000,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Electromagnetic Biology and Medicine","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1080/15368378.2026.2748639","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Differences in the dielectric properties of normal and cancer tissues provide invaluable information for distinguishing them. The open-ended coaxial probe technique is a recognized method for measuring the dielectric properties of normal and cancerous tissues. Machine learning is widely used to classify these tissues on the basis of their dielectric properties. However, the current classification technique is error‑prone, as selecting an insufficient number of features may result in diminished accuracy, whereas selecting an excessive number can lead to overfitting in classification models. This study systematically investigated the impact of noise and individual variability, with particular emphasis on how the number of frequency points, which represents the features, influences the accuracy of cancer identification. The K-nearest neighbor (KNN) algorithm was used to analyze the dielectric properties, and the model was generalized to phantoms. Results demonstrate that as the number of frequency points increases, accuracy stabilizes and improves. However, accuracy gradually plateaued and slightly decreased with excessive frequency points, suggesting potential overfitting. A comprehensive analysis recommends using 20 frequency points for accurate tissue identification. When generalized to phantom dielectric properties data, the model misclassified only one phantom. The dielectric properties offer valuable insights into medical diagnostics. The KNN was effective in distinguishing between normal and cancer tissues. This study also provides practical recommendations for cost-effective dielectric properties analysis.
期刊介绍:
Aims & Scope: Electromagnetic Biology and Medicine, publishes peer-reviewed research articles on the biological effects and medical applications of non-ionizing electromagnetic fields (from extremely-low frequency to radiofrequency). Topic examples include in vitro and in vivo studies, epidemiological investigation, mechanism and mode of interaction between non-ionizing electromagnetic fields and biological systems. In addition to publishing original articles, the journal also publishes meeting summaries and reports, and reviews on selected topics.