African recommendations for diagnosis and management of systemic juvenile idiopathic arthritis (sJIA) - a PAFLAR initiative.

IF 2.3 3区医学 Q1 PEDIATRICS

Pediatric Rheumatology Pub Date : 2026-10-13 DOI:10.1186/s12969-026-01238-z

Soad Hashad, Angela Nyangore Migowa, Ahmed Seri, Ourida Gacem, Ali Sobh, Hala Etayari, Eman A Almsillati, Angelo Ravelli, Pierre Quartier, Ayodele Faleye, Waleed Hassan, Doaa Mosad, Elisa Palalane, Temesgen Teferi, Yaninga Halwani Fuseini, Mohammed Hassan, Hanna Lishan, Wassila Messadi, Madeleine Ngandeu, Yassmin Taha, Wafa Hamdi, Samah Ismail, Hanane Lassoued Ferjani, Chafia Makhloufi Dahou, Yasmine Makhlouf, Samy Slimani, Christiaan Scott, Djohra Hadef

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引用次数: 0

Abstract

Objectives: To develop evidence-based recommendations for diagnosis and treatment of children and adolescents with systemic juvenile idiopathic arthritis (sJIA), taking into consideration the socioeconomic status and availability of medications in African countries.

Methods: A steering group composed of five PAFLAR members formulated questions in PICO format (Patient/Population, Intervention, Comparison, Outcome), conducted a systematic literature review, and identified experts in pediatric rheumatology throughout Africa. The Delphi method was used to reach consensus among the experts on the recommendations for diagnosis and treatment of sJIA patients.

Results: The online Delphi questionnaire was sent to the 22 experts selected by the steering committee, who were asked to vote for each statement and to provide their suggestions for modifications or rewording. A 100% response rate was obtained. A minimum agreement of 70% among the voting panel was required. A total of 15 recommendations were formulated, 4 regarding diagnosis and 11 regarding treatment. The percentage of agreement with the recommendations ranged from 72.7% to 95%.

Conclusion: We present the first African recommendations for diagnosis and management of sJIA. The feedback about the application of these recommendations in pediatric rheumatology centers will serve as the basis for future revisions in the light of African-specific experiences and insights.

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非洲系统性青少年特发性关节炎（sJIA）的诊断和管理建议- PAFLAR倡议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Rheumatology PEDIATRICS-RHEUMATOLOGY

CiteScore

4.10

自引率

8.00%

发文量

审稿时长

>12 weeks

期刊介绍： Pediatric Rheumatology is an open access, peer-reviewed, online journal encompassing all aspects of clinical and basic research related to pediatric rheumatology and allied subjects. The journal’s scope of diseases and syndromes include musculoskeletal pain syndromes, rheumatic fever and post-streptococcal syndromes, juvenile idiopathic arthritis, systemic lupus erythematosus, juvenile dermatomyositis, local and systemic scleroderma, Kawasaki disease, Henoch-Schonlein purpura and other vasculitides, sarcoidosis, inherited musculoskeletal syndromes, autoinflammatory syndromes, and others.