Educational disparities in prostate cancer survival: a retrospective cohort study from Mexico City.

IF 3.9 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Salud Publica De Mexico Pub Date : 2026-10-10 DOI:10.21149/17890

Jesús Gibran Hernández-Pérez, Hortensia Reyes-Morales, Abraham Valenzuela-Sánchez, Martin Lajous, Francisco Rodríguez-Covarrubias, Lucino Iván Espin-Arellano, Evangelina Morales-Carmona, Hugo Manzanilla-García, Luisa Elvira Torres-Sánchez

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引用次数: 0

Abstract

Objective: To evaluate the relationship between educational level and prostate cancer (PC) survival and explore the role of histological differentiation and reasons for PC testing on this association.

Materials and methods: A retrospective cohort was constructed by linking data from men diagnosed with PC between 2011 and 2014 in two secondary care and four tertiary-care hospitals in Mexico City with the National Death Registry, with follow-up through December 2021. Educational level, reasons for testing (symptomatic vs preventive), and histological differentiation were obtained through structured questionnaires. Overall survival (OS) and PC-specific survival (PCSS) at five and eight years were estimated using Kaplan-Meier curves, and PC mortality was evaluated using Cox proportional hazards models.

Results: During a median follow-up of 8.34 years, OS was 81%, and PCSS was 85%. Lower educational level was associated with higher PC mortality (adjusted HR 2.30; 95%CI: 1.16,4.54). The highest mortality was observed among men with low education and poorly differentiated tumors or among those who underwent screening due to the presence of prostate symptoms.

Conclusions: Educational level was the strongest predictor of PC survival, underscoring the importance of targeted health education to improve preventive care, informed decision-making, and treatment adherence.

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来源期刊

Salud Publica De Mexico PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.30

自引率

21.70%

发文量

审稿时长

34 weeks

期刊介绍： Salud Pública de México se crea en 1959 y comienza a publicarse bimestralmente a partir de 1961; en 1988 inicia una nueva época en la que se refuerza su carácter de publicación científica con evaluación por pares. Es una revista publicada por el Instituto Nacional de Salud Pública (INSP), organismo descentralizado de la Secretaría de Salud de México, dedicado a la investigación, docencia y difusión del conocimiento en salud pública. El INSP, de acuerdo con la normatividad internacional, otorga a la revista independencia editorial.