Accelerometry-based comparison of functional outcomes across total and partial knee and hip arthroplasty : a propensity-matched UK Biobank Study.

IF 5.5 2区 医学 Q2 CELL & TISSUE ENGINEERING
Sevasti Panagiota Glynou, Omar Musbahi, Sara Sousi, Justin P Cobb
{"title":"Accelerometry-based comparison of functional outcomes across total and partial knee and hip arthroplasty : a propensity-matched UK Biobank Study.","authors":"Sevasti Panagiota Glynou, Omar Musbahi, Sara Sousi, Justin P Cobb","doi":"10.1302/2046-3758.1510.BJR-2025-0603.R1","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>To evaluate objectively measured physical activity after hip and knee arthroplasty using accelerometry, by comparing bone-preserving procedures with total athorpalsties rthorpalsties and benchmarking both against non-arthritic controls.</p><p><strong>Methods: </strong>This observational study was conducted within the UK Biobank. Adults aged 40 to 69 years with total knee arthroplasty (TKA), unicompartmental knee arthroplasty (UKA), total hip arthroplasty (THA), or hip resurfacing (HR) were identified through linked hospital records and completed seven-day wrist-worn accelerometry (Axivity AX3). Outcomes included adjusted daily step count (primary), peak cadence, moderate-to-vigorous physical activity (MVPA), and Euclidean Norm Minus One (ENMO). Surgical groups were propensity score-matched to non-arthritic controls on demographics, lifestyle factors, and comorbidities. Direct comparisons between procedure types were examined using both propensity-matched analyses and complementary multivariable regression, and adjusted for demographic and clinical covariates. Subgroup analyses considered < 12 months and ≥12 months post-surgery.</p><p><strong>Results: </strong>A total of 2,283 participants were included (TKA = 860, UKA = 162, THA = 1,168, HR = 93). Compared with matched controls, TKA and THA patients showed persistently lower activity, while UKA and HR achieved levels similar to controls. In the knee cohort, UKA patients walked significantly more steps/day than TKA (9,150 vs 7,920; + 15.5%, p < 0.001) with higher cadence. In the hip cohort, HR patients outperformed THA (10,122 vs 9,139 steps/day; + 10.6%, p = 0.032) and demonstrated higher peak cadence, and HR remained comparable to controls. All groups fell within the 'somewhat active' to 'active' step-count range (7,500 to 12,499 steps/day).</p><p><strong>Conclusion: </strong>UKA and HR are associated with higher postoperative activity compared with total arthroplasty (TKA, THA). Accelerometry provides an objective, scalable assessment of functional recovery, highlighting procedure-specific differences that should be considered alongside implant longevity when selecting surgical options.</p>","PeriodicalId":9074,"journal":{"name":"Bone & Joint Research","volume":"15 10","pages":"1213-1227"},"PeriodicalIF":5.5000,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659690/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bone & Joint Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1302/2046-3758.1510.BJR-2025-0603.R1","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CELL & TISSUE ENGINEERING","Score":null,"Total":0}
引用次数: 0

Abstract

Aims: To evaluate objectively measured physical activity after hip and knee arthroplasty using accelerometry, by comparing bone-preserving procedures with total athorpalsties rthorpalsties and benchmarking both against non-arthritic controls.

Methods: This observational study was conducted within the UK Biobank. Adults aged 40 to 69 years with total knee arthroplasty (TKA), unicompartmental knee arthroplasty (UKA), total hip arthroplasty (THA), or hip resurfacing (HR) were identified through linked hospital records and completed seven-day wrist-worn accelerometry (Axivity AX3). Outcomes included adjusted daily step count (primary), peak cadence, moderate-to-vigorous physical activity (MVPA), and Euclidean Norm Minus One (ENMO). Surgical groups were propensity score-matched to non-arthritic controls on demographics, lifestyle factors, and comorbidities. Direct comparisons between procedure types were examined using both propensity-matched analyses and complementary multivariable regression, and adjusted for demographic and clinical covariates. Subgroup analyses considered < 12 months and ≥12 months post-surgery.

Results: A total of 2,283 participants were included (TKA = 860, UKA = 162, THA = 1,168, HR = 93). Compared with matched controls, TKA and THA patients showed persistently lower activity, while UKA and HR achieved levels similar to controls. In the knee cohort, UKA patients walked significantly more steps/day than TKA (9,150 vs 7,920; + 15.5%, p < 0.001) with higher cadence. In the hip cohort, HR patients outperformed THA (10,122 vs 9,139 steps/day; + 10.6%, p = 0.032) and demonstrated higher peak cadence, and HR remained comparable to controls. All groups fell within the 'somewhat active' to 'active' step-count range (7,500 to 12,499 steps/day).

Conclusion: UKA and HR are associated with higher postoperative activity compared with total arthroplasty (TKA, THA). Accelerometry provides an objective, scalable assessment of functional recovery, highlighting procedure-specific differences that should be considered alongside implant longevity when selecting surgical options.

基于加速度计的全膝关节和部分膝关节和髋关节置换术的功能结果比较:一项倾向匹配的英国生物库研究。
目的:通过比较保骨手术与全膝关节置换术和全膝关节置换术,并将两者与非关节炎对照进行比较,客观地评估髋关节置换术后使用加速度计测量的身体活动。方法:本观察性研究在英国生物银行进行。年龄在40 - 69岁之间,接受全膝关节置换术(TKA)、单室膝关节置换术(UKA)、全髋关节置换术(THA)或髋关节置换术(HR)的成年人通过相关的医院记录和完成的7天腕带加速度计(Axivity AX3)进行鉴定。结果包括调整后的每日步数(主要)、峰值节奏、中高强度体力活动(MVPA)和欧几里得Norm - 1 (ENMO)。手术组在人口统计学、生活方式因素和合并症方面与非关节炎对照组的倾向评分相匹配。使用倾向匹配分析和互补多变量回归检查手术类型之间的直接比较,并根据人口统计学和临床协变量进行调整。亚组分析考虑术后< 12个月和≥12个月。结果:共纳入受试者2283人(TKA = 860, UKA = 162, THA = 1168, HR = 93)。与匹配的对照组相比,TKA和THA患者的活动持续降低,而UKA和HR达到与对照组相似的水平。在膝关节队列中,UKA患者每天行走的步数明显多于TKA患者(9150 vs 7920; + 15.5%, p < 0.001),且步数更高。在髋关节队列中,HR患者的表现优于THA(10122步/天vs 9139步/天;+ 10.6%,p = 0.032),并且表现出更高的峰值节奏,HR与对照组相当。所有组的步数都在“有些活跃”到“活跃”之间(每天7500到12499步)。结论:与全关节置换术(TKA, THA)相比,UKA和HR与更高的术后活动相关。加速度计提供了一个客观的、可扩展的功能恢复评估,强调了在选择手术方案时应考虑植入物寿命和手术程序的具体差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Bone & Joint Research
Bone & Joint Research CELL & TISSUE ENGINEERING-ORTHOPEDICS
CiteScore
7.40
自引率
23.90%
发文量
156
审稿时长
12 weeks
期刊介绍: The gold open access journal for the musculoskeletal sciences. Included in PubMed and available in PubMed Central.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书