Comparison between operative management versus non-operative management in patients with solid organ blunt abdominal injury in the National Trauma Registry of Iran.
Sara Mirzamohamadi, Mohammad Navid HajiAbbasi, Somayeh Ghorbani, Payman Salamati, Mohammadreza Zafarghandi, Vafa Rahimi-Movaghar, Esmaeil Fakharian, Seyed Houssein Saeed-Banadaky, Vahid Hoseinpour, Mehdi Nasr Isfahani, Amir Ghadiphasha, Sobhan Pourmasjedi, Seyed Mohammad Piri, Khatereh Naghdi, Seyed Amir Miratashi Yazdi
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引用次数: 0
Abstract
Background: Trauma is one of the leading causes of death worldwide. Severe abdominal injuries cause one-fifth of injury mortality. Non-operative management (NOM) or operative management (OM) is a primary challenge in abdominal injuries. In this study, we aimed to compare NOM and OM outcomes in patients with solid organ blunt abdominal injuries in the National Trauma Registry of Iran (NTRI).
Method: This cross-sectional study was conducted with data from the NTRI from 24 July 2016 to 21 May 2023. All patients with a solid organ abdominal injury by road traffic crash, falls, hit or bodily force, and assault with blunt objects were admitted to trauma registry member hospitals across the country, according to the NTRI criteria included in this study.
Results: Among 358 patients, liver, spleen, and kidney single-organ injuries were managed non-operative more than operative. Among multi-organ abdomen injuries, kidney injuries alongside spleen or liver injuries are managed non-operative more than operative. In the multiple regression model on the matched cohort (102 NOM with 102 OM), moderate or severe Glasgow Coma Scale (GCS) had 16.79 times more chance of Intensive Care Unit (ICU) admission than mild GCS [OR: 16.79, 95% CI (2.06, 137.22), P = 0.008]. Also, hypovolemia increased the chance of death 12.9 times [OR: 12.90, 95% CI (2.20, 75.53), P = 0.005]. In addition, for every 1-year increase in age, the odds of the death occurring increased 1.07 [OR: 1.07, 95% CI (1.02, 1.12), P = 0.005].
Conclusion: We observed the non-inferiority of NOM than OM due to the outcomes. Although the liver, spleen, and kidney are mainly managed by non-operatives.
背景:创伤是世界范围内死亡的主要原因之一。严重的腹部损伤导致了五分之一的伤害死亡。非手术治疗(NOM)或手术治疗(OM)是腹部损伤的主要挑战。在这项研究中,我们的目的是比较NOM和OM在伊朗国家创伤登记处(NTRI)实体器官钝性腹部损伤患者中的结果。方法:采用2016年7月24日至2023年5月21日NTRI的数据进行横断面研究。所有因道路交通事故、跌倒、撞击或身体力量以及钝器攻击而造成腹部固体器官损伤的患者,均根据本研究中包含的NTRI标准,被送往全国各地的创伤登记成员医院。结果:358例患者中,肝、脾、肾单脏器损伤非手术处理多于手术处理。在多器官腹部损伤中,肾脏损伤伴脾或肝损伤的非手术治疗多于手术治疗。在匹配队列(102 NOM + 102 OM)的多元回归模型中,中度或重度格拉斯哥昏迷量表(GCS)患者入住重症监护病房(ICU)的几率是轻度格拉斯哥昏迷量表患者的16.79倍[or: 16.79, 95% CI (2.06, 137.22), P = 0.008]。此外,低血容量使死亡机会增加12.9倍[OR: 12.90, 95% CI (2.20, 75.53), P = 0.005]。此外,年龄每增加1岁,死亡的几率增加1.07 [OR: 1.07, 95% CI (1.02, 1.12), P = 0.005]。结论:我们观察到NOM与OM在疗效上的非劣效性。虽然肝、脾、肾主要由非手术医师管理。